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BENZENE
FORMULA: C6 H6
SYNONYMS/COMMON NAMES
BENZOL
KNOWN USES:
IN MANUFACTURE OF MEDICINAL CHEMICALS, DYES, ORGANIC COMPOUNDS, ARTIFICIAL LEATHER, LINOLEUM, OIL CLOTH, VARNISHES, LACQUERS, SOLVENT FOR WAXES, RESINS, OILS. USED TO DESTROY SCREWWORM LARVAE IN WOUNDS-VETINARY USE (MERCK 1989).
What is benzene?
Benzene is a colorless liquid with a sweet odor. It evaporates into the air very quickly and dissolves slightly in water. It is highly flammable and is formed from both natural processes and human activities.
Benzene is widely used in the United States; it ranks in the top 20 chemicals for production volume. Some industries use benzene to make other chemicals which are used to make plastics, resins, and nylon and synthetic fibers. Benzene is also used to make some types of rubbers, lubricants, dyes, detergents, drugs, and pesticides. Natural sources of benzene include volcanoes and forest fires. Benzene is also a natural part of crude oil, gasoline, and cigarette smoke.
What happens to benzene when it enters the environment?
Industrial processes are the main source of benzene in the environment.
Benzene can pass into the air from water and soil.
It reacts with other chemicals in the air and breaks down within a few days.
Benzene in the air can attach to rain or snow and be carried back down to the ground.
It breaks down more slowly in water and soil, and can pass through the soil into underground water.
Benzene does not build up in plants or animals.
How can benzene affect my health?
Breathing very high levels of benzene can result in death, while high levels can cause drowsiness, dizziness, rapid heart rate, headaches, tremors, confusion, and unconsciousness. Eating or drinking foods containing high levels of benzene can cause vomiting, irritation of the stomach, dizziness, sleepiness, convulsions, rapid heart rate, and death.
The major effect of benzene from long-term (365 days or longer) exposure is on the blood. Benzene causes harmful effects on the bone marrow and can cause a decrease in red blood cells leading to anemia. It can also cause excessive bleeding and can affect the immune system, increasing the chance for infection.
Some women who breathed high levels of benzene for many months had irregular menstrual periods and a decrease in the size of their ovaries. It is not known whether benzene exposure affects the developing fetus in pregnant women or fertility in men.
Animal studies have shown low birth weights, delayed bone formation, and bone marrow damage when pregnant animals breathed benzene.
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How likely is benzene to cause cancer?
The Department of Health and Human Services (DHHS) has determined that benzene is a known human carcinogen. Long-term exposure to high levels of benzene in the air can cause leukemia, cancer of the blood-forming organs.
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Is there a medical test to show whether I've been exposed to benzene?
Several tests can show if you have been exposed to benzene. There is test for measuring benzene in the breath; this test must be done shortly after exposure. Benzene can also be measured in the blood, however, since benzene disappears rapidly from the blood, measurements are accurate only for recent exposures.
In the body, benzene is converted to products called metabolites. Certain metabolites can be measured in the urine. However, this test must be done shortly after exposure and is not a reliable indicator of how much benzene you have been exposed to, since the metabolites may be present in urine from other sources.
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